Synopsis of the pharmacokinetics, pharmacodynamics, applications, and safety of firocoxib in horses
According to in vitro and in vivo investigations, firocoxib (FX), a second-generation coxib, is a highly selective COX-2 inhibitor in horses.With a COX-1/COX-2 IC50 ratio of 643 in horses, FX spares Glass Markers the COX-1 inhibitory effects.It is approved for the treatment of musculoskeletal problems and lameness in horses and dogs with osteoarthr